Headquartered in Tucson, Arizona, we are
a provider of instruments and reagents for molecular profiling
applications. Our mission is to empower precision medicine at the
local level. Our next-generation sequencing (NGS)-adapted chemistry
and instrument platforms automate sample processing and can quickly, robustly,
and simultaneously profile hundreds or thousands of molecular targets from
samples a fraction of the size required by competitive technologies, enabling
customers to do more molecular profiling with less sample.
Additional information about us is available at www.htgmolecular.com.
The role of Senior Research Scientist is responsible
for contributing scientific and technical expertise to initiate, conduct and
direct complex product and technology research, and provide support to the development
of novel products. This individual will interact with and support various internal
and external stakeholders, and may act as a liaison with internal functions
and/or outside collaborators and partners.
This role requires an in-depth understanding of first-principle
mechanisms applicable to molecular biology, cancer biology, gene expression
profiling and next generation sequencing (NGS) technologies. The role will also
require participation in optimizing and improving current commercial assays and
establishing workflows, processes and technologies by providing scientific,
technological and subject matter expertise as needed. The incumbent will
lead execution of research, clinical and analytical laboratory studies from
study design through final data analysis and study report.
- Provides strong scientific expertise
in the areas of cancer biology, molecular genetics, gene expression profiling
and NGS analytical methods for evaluating tumor-associated biology.
- Maintains up-to-date knowledge in the
above areas, and proactively proposes and implements application of new ideas
and concepts in the context of development programs.
- Independently performs a wide variety
of experiments, techniques and assays to advance technology development,
product development, collaborations and troubleshooting.
- Collaborates with peers, or works
independently to investigate and address highly complex product-related
biological and technology development issues.
- Provides subject area expertise
(biology, technology, process, etc.) directly or identifies a subject matter
expert to consult with the team as needed.
- Authors research protocols and
reports for a wide range of studies, including feasibility, exploratory,
clinical and analytical studies, to be executed within the Research and
Development function as well as externally in collaborators’ laboratories.
- Provides scientific input to help set
the direction for product and process improvements.
- Authors abstracts, conference posters
and talks, as well as publications.
- Provides internal education about
products and technology to new and existing employees at varied experience and
technical knowledge levels.
- Provides technical oversight to
remove roadblocks and coordinates with Department Head or others as necessary
to complete laboratory studies on time and on budget.
- A minimum of 6 years
of relevant industrial or post-doctoral experience (industrial experience
- Strong background
in biochemistry and molecular biology methods with experience in assay
development, nucleic acid isolation, purification and quantitation, qPCR,
RNA-Seq, gene expression profiling, RNA techniques, and next generation
sequencing (NGS) assays.
Knowledge, Skills and
- Knowledge of
tissue-based and non-tissue-based analytical methods for evaluating
tumor-associated biology and/or immune response mechanisms. Experience in
cancer-focused research through published research.
- Strong familiarity with a variety of next-generation
sequencing workflows including library preparation, instrumentation, and data
- Ability to perform highly
complex research independently in a systematic manner. Proven track record of
subject matter expertise in relevant research areas demonstrated through
publications and product R&D.
- High level of proficiency with basic statistical
methods and mathematics, data-analysis software and standard statistical tests.
- Must have excellent
written and verbal communication and presentation skills (including technical writing).
- Detail-oriented and
highly organized while demonstrating effective time management to meet
deadlines within budgetary constraints. Must be able to work effectively
on multiple programs in a fast-paced environment with an appropriate level of
and Environmental Requirements:
Some weekend and evening
work may be required in order to meet deadlines. Work is indoors in a
seasonally heated and air-conditioned environment. The position is sedentary and
requires lab work, typing and the ability to move objects weighing up to 25
lbs. Occasional travel is required.
Nestled at the
foothills of the majestic Catalina Mountains, and ringed by 4 other mountain
ranges, a young and family friendly modern metropolis, Tucson offers 276 days
of sunshine, unparalleled golf, museums, historic sites and hiking trails
where one can experience the wide variety of animal and plant life of the
Sonoran Desert, one of the most biodiverse spots on the planet.
competitive salaries and an attractive benefits package including 100% employer
paid medical and dental benefits, long term disability and life insurance, an
employee stock purchase plan, and the unique ability to work with cutting edge technological
Please apply here
HTG is an Equal
HTG Molecular Diagnostics, Inc. is an EEO employer - M/F/Vets/Disabled