Translational Biology - 2019 Summer Internship
C4 Therapeutics Inc Watertown, MA
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Overview:

  • Approximately 3-5 college interns for summer 2019
  • Begin in June and last approximately 10 weeks, depending on semester/trimester timing
  • Interns will work on a specific project(s) throughout the summer
  • Interns will give a 20-min presentation in mid-August
  • HR will coordinate bi-weekly brown bag lunch events with speakers from different teams/areas
  • HR will hold an interview, resume, and phone screen training
  • We will host several social activities

 

OPPORTUNITIES

In each of these roles you will learn the process of how large numbers of anticancer compounds are screened in order to select the most appropriate for clinical development.  You will interact with each of the various scientific disciplines to see what their responsibilities are and what a working day is like.  This will provide an understanding for the various opportunities that exist in a biotechnology setting and the education/experience required to work in those roles.

 

IN VIVO PHARMACOLOGY (IVP)

The IVP group is looking for a student interested in learning about, and participating in, the development of small molecule cancer drugs using a variety of in vitro and in vivo (animal) systems.  In this 10-week program you will: 

  • Work on a project pre-designed for you to learn how animal tumor models are chosen and applied for drug testing. 
  • You will not work directly with animals, but you will be taught the importance of pharmacokinetics and pharmacodynamics in drug selection and how we utilize modeling to support animal study design. 
  • You will make your own hypotheses, develop assays and test these using cancer cell lines and historical tumor samples and a variety of cancer biology assays including qPCR, immuno-assays and proteomics.
  • Based on these results you will participate in the design and management of animal studies, analyze associated data and present your findings at team meetings and the end of summer Intern Seminar event

 

REQUIREMENTS

  • Strong work ethic and desire to learn 
  • General understanding of cancer biology
  • Experience with pipettes and basic tissue culture practices
  • Experience with calculating/performing basic dilutions
  • Helpful to have prior experience with measuring protein and RNA levels (immunoassays, qPCR)
OR
 
 
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