Research Associate, Cell Pharmacology
C4 Therapeutics Inc Watertown, MA
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About C4 Therapeutics

C4 Therapeutics is pioneering a new class of drugs. C4’s technology platform produces small molecule drugs that harness machinery already present in cells to selectively target disease-relevant proteins for degradation. Our approach has the potential to address a broad range of diseases including cancer, infectious disease, and autoimmune disorders.

Responsibilities

  • Support cell-based compound screening efforts for small molecule degrader drug discovery
  • Assist compound profiling operation
    • Operate an acoustic liquid dispenser (Echo) to perform compound dispensing and generate assay ready plates (ARPs)
    • Maintain instruments (e.g. automation system, Echo, Combi, etc)
  • Provide mammalian cell culture support for assay development
    • Maintaining cell lines
    • Validate cell lines via various assay formats
    • Manage cell banking
  • Execute cell-based compound screening assays in the high-throughput format following standard operating procedures
    • Monitor assay performance and perform data QC with strong attention to detail
    • Generate, analyze, and record data with database and software tools
  • Maintain laboratory records, prepare protocols and technical reports, and communicate results in a concise and clear manner
  • Contribute to laboratory organization and maintenance

 

Preferred Qualifications:

  • BS/MS with lab experience in biology or other related disciplines
  • Experience with aseptic technique and mammalian cell culture is required
  • Experience with cell-based assay development is preferred
  • Experience in supporting the discovery of small molecule therapeutics is a plus.
  • Self-motivated, willingness to learn, and strong work ethics
  • Attention to detail with excellent organizational skills, multitasking skills, and communication skills
  • Able to meet timelines and adapt to changes quickly
  • Sense of humor and ability to work in a fast-paced environment
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